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Semaglutide targets GLP-1 receptors only, while tirzepatide is a dual-agonist targeting both GLP-1 and GIP receptors
The similarity between FBF-1 and FBF-2 results in them binding and regulating the same mRNA targets through the conserved FBF-response element (FBE) ( fbf-1 and fbf-2 were first characterized for their role in regulating the sperm to oocyte transition within the hermaphrodite germline through repressing the expression of FEM-3 (Zhang et al., 1997)
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doi: 10.1016/j.diabres.2011.10.029 5 CosentinoFGrantPJAboyansVBaileyCJCerielloADelgadoVet al
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